Protein Molecular Weight Markers
ABclonal Technology GABRD Rabbit pAb
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
ABclonal Technology EPS8 Rabbit pAb
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
ABclonal Technology PTCH1 Rabbit pAb
This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly.
ABclonal Technology TCTE1 Rabbit pAb
Predicted to be involved in flagellated sperm motility. Predicted to be located in sperm flagellum.
ABclonal Technology RPL24 Rabbit pAb
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from S. cerevisiae, however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
S2 Media 15x100mm Chameleon™ COLOREX™ Staph aureus, 10/pack
Chameleon™ COLOREX™ Staph aureus is a selective and differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of Staphylococcus aureus. Test specimens include swabs from teguments, wounds, or soft tissue. It can also be used in the detection of S. aureus in the analyses of food products for human consumption, animal feed, and in environmental samples. Concomitant cultures should be performed to recover organisms for further microbiological testing or epidemiological typing. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ Staph aureus should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
ABclonal Technology GABRG1 Rabbit pAb
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4.
S2 Media 15x100mm Chameleon™ COLOREX™ Orientation and Tryptic Soy Agar with 5% Sheep Blood (Orient|BAP), Biplates, 10/pack
Chameleon™ COLOREX™ Orientation and Tryptic Soy Agar with 5% Sheep Blood (Orient|BAP) Biplates: TSA w/ 5% Sheep Blood (Blood Agar) is a non-selective, differential growth medium utilized for the isolation and cultivation of non-fastidious and fastidious organisms. Hemolytic response can be utilized to differentiate microorganisms. TSA w/ 5% Sheep Blood is not the medium of choice for anaerobes. Chameleon™ COLOREX™ Orientation is a non-selective, differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of uropathogens associated with urinary tract infections (UTI). • Product complies with BAM, CLSI, and USDA reference methods and performance criteria.• Media should be used by trained professionals within a laboratory setting.• For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
ABclonal Technology MRPL18 Rabbit pAb
This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16.
ABclonal Technology SLC6A9 Rabbit pAb
The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft.
ABclonal Technology ZC3H14 Rabbit pAb
The protein encoded by this gene is a poly(A)-binding protein that can affect gene expression and poly(A) tail length. The encoded protein may influence mRNA stability, nuclear export, and translation.
New England Biolabs, Inc. Blue Prestained Protein Standard, Broad Range (11-250 kDa) – 750 gel lanes
The Blue Prestained Protein Standard, Broad Range is a mixture of highly pure, recombinant, prestained proteins, covalently coupled with a blue chromophore, that resolves into 11 sharp bands when electrophoresed.
ABclonal Technology EMR2 Rabbit pAb
This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ABclonal Technology KSR1 Rabbit pAb
Enables 14-3-3 protein binding activity, ATP binding activity, and protein C-terminus binding activity. Involved in positive regulation of MAPK cascade. Located in endoplasmic reticulum and membrane. Part of protein-containing complex. Implicated in breast adenocarcinoma. Biomarker of breast cancer.
ABclonal Technology IPO4 Rabbit pAb
Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in DNA replication-dependent chromatin assembly, DNA replication-independent chromatin assembly, and protein import into nucleus. Located in chromatin. Part of protein-containing complex.